Preparation of phyllanthus amarus. 84 mg/100g) as compared .


Preparation of phyllanthus amarus. amarus is an important plant reported in Indian Ayurvedic system of medicine to treat various problems related to Mar 5, 2020 · been on leaves and the aerial parts of other Phyllanthus species; Phyllanthus amarus that is known to contain higher concentration of phyllanthin [ 15 ]. Collection, Identification, Preparation of Phyllanthus amarus Fresh leaves of Phyllanthus amarus were collected from the riverbanks of Amuri in Nkanu West Local Government Area in Enugu State Nigeria, in the month of October –November, 2021. 3%, respectively (Tripathi et al. Phyllanthus amarus, an important herbaceous medicinal plant, belongs to the large and complex genus Phyllanthus in the Euphorbiaceae family [Figure 1]. amarus. While the standardized methanolic extract of Phyllanthus amarus leaf (Methanol extract Jul 4, 2024 · Phyllantus amarus: Family: Phyllanthaceae: Origin: Tropical and subtropical regions of Africa, Asia, and South America: Description: Phyllanthus amarus is a small, erect herb that grows up to 60 cm tall. Phyllanthus amarus is a leafy herbal plant found in tropical regions in the Americas, Africa, India, China,Sri Lanka and South East Asia. Jul 7, 2022 · Phyllanthus amarus is an annual herb naturally occurring in tropical and subtropical regions of Central and South Asia, up to an altitude of 800–1000 m MSL. The herbal ointment made with Sida acuta extract from both extractants showed significantly different activity (P < 0. ” It is commonly called as “stone breaker. 05), against the test pathogens when compared to the reference medication (Madecassol®). Shows leaves of A: Sida acuta, B: Phyllanthus amarus and C: Parkia biglobosa. Male flower in groups of 1-3 where and female are solitary. Introduction Oct 1, 1988 · In a preliminary study, carriers of hepatitis B virus were treated with a preparation of the plant Phyllanthus amarus for 30 days. Zubair and others published Chemical constituents and antimicrobial properties of Phyllanthus amarus (Schum & Thonn) | Find, read and cite all the research you need on Dec 8, 2022 · 2. Fruits ofPhyllanthus paracetamol. Feb 28, 2012 · The micropropagation protocol for Phyllanthus amarus, an important medicinal herb used widely for the treatment of hepatitis in ethnomedicinal systems, was standardized with shoot tip and single 4. Plant material and preparation of extracts. Preparation of Extract Plant material was washed with water and then allowed to dry in shade for about 3 to 4 weeks. amarus is an important plant of Indian Ayurvedic system of medicine which is used in the problems of stomach, genitourinary system, liver, kidney and spleen. fraternus, P. College Bhopal. , 2011). ) region. How Phyllanthus Amarus is effective for various diseases is listed in repertory format. Their effectiveness as an ointment in treating the aforementioned illnesses has not yet May 14, 2021 · Although P. Dried plant Oct 16, 2022 · PDF | On Oct 16, 2022, Yakubu Ojochenemi and others published Purification and Determination of Antioxidant Effects of Ethanol Extract Fractions in Phyllanthus amarus Leaves | Find, read and cite Aug 17, 2020 · The sodium content (11. However, available literature revealed that there is a need to summarize the Sep 1, 2023 · The minimum bactericidal concentration (MBC) and minimum inhibitory concentration (MIC) values for the plant extracts were both low. successively in 98% Methanol and water for 48hrs each. , 2015). Tamarindus indica Extracts of Phyllanthus amarus The standardized extract of Phyllanthus amarus whole plant (water extract) Reference No: SR/KN/CL/1/2012-L12030241, was procured as a gift sample from Chemiloids Ltd. , belonging to this genus, is one such significant medicinal plant that grows throughout the world including India. Phyllanthus amarus has been classified among plants with a low toxicity with the LD50 averaging 200 mg/ kg/ day [7]. The selected plants namely ;Phyllanthus amarus (whole plant) used in the present study was collected from the Allepey,Kerala and Jaipur,Rajasthan and Phyllanthus amarus (whole plant) was authenticated by BSI Pune. amarus has been reported to be useful in the treatment of dropsy, jaundice, diarrhoea, dysentery, intermittent fevers, urinogenital diseases, scabies, ulcers, and wounds. 163µg The Indigenous plant Phyllanthus amarus were collected from different locations of Bhopal (M. P. amarus) has been used as a herbal medicine, particularly for liver support, in many countries and its extracts have been shown to possess potent antioxidant and anticancer properties in vitro. . Names of Phyllanthus Amarus in various languages of the world are also given. amarus (EPA) in LPS-activated BV2 microglial cells. Commons names for this plant include gale of the wind , carry me seed , seed on the leaf , pick-a-back , [ 1 ] Bhuiavla (Hindi), Bhuiamla (Bengali), [ 2 ] stonebreaker , dukung anak (Malay). It is used in the traditional and folk medicines for the treatment of jaundice, asthma, hepatitis, tuberculosis, ulcer and urinary diseases. F. Similar types of studies were made by Sharma et al (1993) and Murali et al. The present study was carried out to investigate the effects of 80% Dec 30, 2015 · Plant collection and preparation. Phyllanthus amarus has been used widely in various traditional medicines to treat swelling, sores, jaundice, inflammatory diseases, kidney disorders, diabetes and viral hepatitis, while its pharmacological and biochemical mechanisms underlying its anti-inflammatory properties have not been well investigated. amarus leaf and seed extracts. It comprises slender, leaf-bearing branchlets, distichous leaves. amarus [ 43 ]. amarus antimalarial activity depends on the dose of the extract administered, the chemotherapeutic effect of P. Feb 5, 2014 · 2. It is bitter, astringent, stomachic, diuretic, febrifuge and antiseptic. The powdered leaves (1000 g) were macerated with petroleum ether to remove fatty substances; the marc was further exhaustively extracted with 95% ethanol for 3 d (3 × 3 l) by cold percolation method and centrifugation at 10 000 rev min −1. The flowers of Phyllanthus amarus are yellowish, whitish or greenish. The HPTLC method for the quantitative estimation of Phyllanthin was validated with regard to their specificity, precision, accuracy and linearity. Phytochemical studies carried out on the aqueous and ethanolic leaf extract of Phyllanthus amarus revealed the presence of bioactive compounds namely, cardiac glycosides, coumarins, saponins, Nov 30, 2021 · Phyllanthus amarus Schum. Feb 4, 2020 · The quantitative phytochemical composition, bioactive constituents of ethanol extract of Phyllanthus amarus leaves were determined. 22 of 37 (59%) treated patients had lost hepatitis B surface antigen when tested 15-20 days after the end of the treatment compared with only 1 of 23 (4%) placebo-treate … overdose can lead to potentially lethal liver and in severe Eclipta alba, Phyllanthus amarus, Phyllanthus debilis cases leads to death [2-5]. and Thonn. Moreover, traditional decoction of this fresh plant material appeared better In the present study, 80% ethanol extract of Phyllanthus amarus was used to generate tumor lysate (TLY) derived from HCT 116 and MCF-7 cancer cell lines via induction of apoptosis. Dhalwal et al. 4. Nov 18, 2011 · P. amarus were Abstract Background. EL-Desoky 3 , Shanaz O. 2. Jul 25, 2018 · Background Phyllanthus amarus has been used widely in various traditional medicines to treat swelling, sores, jaundice, inflammatory diseases, kidney disorders, diabetes and viral hepatitis, while its pharmacological and biochemical mechanisms underlying its anti-inflammatory properties have not been well investigated. 30g each of the pulverized plant was macerated . Tamarindus indica. Fruit of Phyllanthus amarus are depressed, globose, with smooth capsule present under Phyllanthus amarus also have antiseptic, diuretic, antiviral, anti-diabetic, hypertensive, and antipyretic parcels and is used in the treatment of hostility, diarrhea, dysentery, injuries, ulcers, and urogenital conditions [6]. Meselhy 1 , Ola E. List of various diseases cured by Phyllanthus Amarus. The plant is native to tropical and subtropical regions around the world including various countries in South America, Africa, India, China, Sri Lanka and South East Asia. urinaria, and P. 2. Aug 1, 2021 · The traditional mode of preparation as well as the post-harvest conditions could influence both phytochemical composition and biological activity. crude extracts were weighed into separate beakers and dispersed in DMSO to derive concentrations of 25 mg -L1, 50 mg L-1, 100 mg L and 200 mg L-1. Similar studies have been reported in Phyllanthus fraternus (Kavit et al. amarus with water, methanol, ethyl acetate and petroleum ether (Awasthi et al. (2006) developed a HPTLC densitometric method for simultaneous quantitation of phyllanthin, hypophyllanthin, gallic acid, and ellagic acid in the whole plant of P. The plant was identified and authenticated by Oct 6, 2020 · Phyllanthus amarus Schum. (Spurge family). Quantification of the marker may also reflect the Keywords: phyllanthus amarus, euphorbiaceae, phytochemical screening Introduction [Phyllanthus amarus belonging to family Euphorbiaceae [1]. (2022) study of the proximate and phytochemical composition of Phyllanthus amarus provide evidence for this. Fresh leaves of Phyllanthus amarus Schum were collected from the campus of the University of Ibadan, Nigeria in March 2012. R. 95 mg/100g reported by [37] and in other hand higher in raw C. (2001) in Phyllanthus amarus. , Vijaywada. amarus were dried in air followed by tray drier under control conditions and powdered. , 2013) and different species of Phyllanthus leaf extracts for preliminary phytochemical evaluation (Gopinath et al. belongs to the family Euphorbiaceae, commonly known as “Bhooamalakee” or “Bhuti”, traditionally being used for the treatment of gastrointestinal troubles, kidney, liver problems, etc. It is sometimes found Sep 1, 2013 · Three of the commonly used Phyllanthus herbs in preparation of herbal medicines are P. Preparation of plant crude extracts Sida acuta, Phyllanthus amarus, and Parkia biglobosa leaves were rinsed with distilled water and dried for four weeks in the shade to Fig. The observations indicated that Phyllanthus amarus as a potential diuretic Jul 30, 2022 · Collection, Identification, Preparation of Phyllanthus amarus . Mar 5, 2020 · Phyllanthin and related lignans were found to be responsible, at least in part, for most of the activity of Phyllanthus species. Phyllanthus amarus Schum. The plant was identified and authenticated at the Forestry Research Institute of Nigeria (FRIN), Ibadan, Nigeria with voucher number 108345. Abdel-Sattar 1 , Sahar El-Mekkawy 2 , Ahmed M. tenellus, P. Apr 6, 2012 · Unlabelled: Phyllanthus amarus Schum. The flowers are numerous, small and green, and the fruits are tiny, smooth capsules containing seeds Phyllanthus amarus bears leaves on branchlets, with subsessile and round base. Native Regions: Phyllanthus amarus is native to tropical regions, including parts of Central and South America, Africa, and Southeast Asia. amarus has a long history of use in the traditional system of medicine for over 2000 years owing to its wide array of secondary metabolites that confer significant medicinal attributes. Aqueous extract of Phyllanthus amarus (P. Phyllanthus amarus, is a small, erect, annual glabrous herb with 30-50 cm in length [2]. Methods BV2 microglial cells c for 24 h, pre-treated with EPA Phyllanthus amarus (Phyllanthus niruri) is an herbaceous plant of Euphorbiaceae family. citratus (9. Jul 1, 2020 · Background Phyllanthus amarus has been shown to attenuate lipopolysaccharide (LPS)-induced peripheral inflammation but similar studies in the central nervous system are scarce. Indeed, the use of fresh aerial parts of Phyllanthus amarus yielded the best antioxidant and antihyperglycemic potential. Global Spread: Due to its adaptability and medicinal significance, Phyllanthus amarus has been introduced to various tropical and subtropical regions around the world. 15 mg/100g) of raw P. amarus, P fraternus and P. & Thonn. Iteeeeeed is a member of Euphobiaceae family. Phyllanthus amarus is one of the most important medicinal plant in tropical and subtropical nations which are used for stomach, liver, kidney Uses, Benefits, Cures, Side Effects, Nutrients in Phyllanthus Amarus. In general administration f and Boerhaavia diffusao are well known for their paracetamol damage hepatocytes as they metabolise the hepatoprotective effects [10-13]. niruri L. composition of Phyllanthus amarus. virgatus) are listed in Table 2. urinaria obtained from Malaysia and Indonesia by using a validated reversed phase high performance liquid chromatography (RP-HPLC) method. Phyllanthus amarus (P. The species has a long history of use and is an important plant in the Ayurvedic medical system in the treatment of diseases of liver, genitourinary system, kidney and stomach 15 , 16 . Fresh samples of Phyllanthus amarus were collected in the morning in the months of May to August from the natural habitat in Sagamu, Ogun state, Nigeria. , 2006). The lignan phyllanthin renders hepatoprotective property to P. Further, this study supports its usage in ethnomedicines for management of diabetes. Phyllanthus amarus. 7 and 97. Jul 7, 2022 · Phyllanthus amarus is an annual herb naturally occurring in tropical and subtropical regions of Central All aspects of preparation of culture media and growth conditions were described Phyllanthus amarus Leaves Extracts Maitrayee Biswas1, Pranabesh Ghosh2*, research investigation it may be concluded that Phyllanthus amarus can be used for the preparation of natural drugs for Feb 27, 2022 · Preparation of P. Aug 19, 2023 · Herbal extracts are a well-known source of therapeutically important bioactive chemicals since they are widely available, relatively inexpensive, and have fewer adverse effects. (family Euphorbiaceae) is a small herb well known for its potent medicinal properties and widely used worldwide. Finally, the absence of in vivo antimalarial evaluation in this study limited the authentication and consideration of the P. , a globally distributed herb is known for its several therapeutic potentials. debilis, P. Keywords: Phyllanthus amarus, extracts, pancreatic amylase inhibitory effects. Phyllanthus niruri also known as Phyllanthus amarus Schum and Thonn, is known as Dukung anak in Malaysia, Iyin Olobe by the Yoruba tribe in Nigeria. The quantitative phytochemical analysis of ethanol extract of Phyllanthus amarus found to be present in this study includes phenol, flavonoid, saponin, tannin and alkaloid. Feb 4, 2020 · Phyllanthus amarus (Family- Euphorbiaceae) is a widely used important medicinal plant in various diseases. 1. Direct extraction with solvents produced extracts with variable yields and contents of lignans the aqueous and ethanolic extract of the leaves of Phyllanthus amarus collected from the University of Benin botanical garden using standard procedures. Abstract. amarus), has recently been reported to have hepatoprotective and immunosuppressive effects on various in Balb/C mice in a dose-dependent way through the inhibition of CD11b/CD18 adhesion, nitric oxide and myeloperoxidase activity release . , 2012). Nov 12, 2022 · Phyllanthus amarus Schum. It is commonly called as “stone breaker. Jan 1, 2015 · Figure 1: Preparation of Phyllanthus amarus ethanolic extract Bhat, et al . The conventional methods of extraction Objective: Herbal ointment containing methanol extract of the aerial part of Phyllanthus amarus was formulated and parameters including antimicrobial properties against some human pathogens such as Bacillus subtilis, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Aspergilus niger were evaluated. 1. urinaria. The leaves are subsessile This study supports the ayurvedic concept that ethanol and hexane extracts of P. The leaves were identified by botanists and a voucher specimen (UIH ADE/003/2012) deposited at the herbarium of the Department of Botany, University of Ibad Jan 2, 2024 · Phyllanthus amarus commonly known as Stonebreaker or Carry Me Seed is a small, herbaceous plant belonging to Phyllanthus genus and Euphorbiaceae Juss. May 11, 2015 · Abstract. Tayaaf Safi Principal Gandhi P. Phyllanthus amarus were investigated using agar well diffusion method for activity against several drug resistant pathogens such as Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus Feb 3, 2014 · The phytochemicals with associated pharmacological activities of six Phyllanthus herbs (P. amarus extracts is good at higher doses (1 600 mg/kg/day). Antiviral properties of Phyllanthus amarus. This plant has been known for its usage in the ‘Ayurvedic’ system of medicine for over 2000 years. Due to the fact Phyllanthin, one of the main and active ingredient in many Phyllanthus species (P. The total content of phenol is 73. The compounds, gallic acid, ellagic acid, corilagin, geraniin, phyllanthin and hypophyllanthin were identified and quantitatively analyzed in the extracts of Phyllanthus amarus and P. : Analgesic and anti-in ammatory property of Phyllanthus amarus ethanolic extract Phyllanthus amarus is a commonly known weed used for the traditional treatment of several aliment. molecules Article Preparation of Lignan-Rich Extract from the Aerial Parts of Phyllanthus niruri Using Nonconventional Methods Meselhy R. The aim of the present study was to investigate the neuroprotective effects of 80% ethanol extract of P. amarus leaf was found to be lower than the value 32. amarus) treatment Mar 4, 2013 · Phyllanthus amarus is a herb belonging to the Phyllanthus genus of the Phyllanthaceae (Euphorbiaceae) family, which is widespread throughout tropical and subtropical countries such as India Proximate analysis of Phyllanthus amarus plant species were studied at the laboratory. The three plants' leaves have been used to treat a variety of illnesses in Ghana, including skin conditions and wound infections. crude extracts were weighed into separate beakers and dispersed in DMSO to derive concentrations of 25 mg -L1, 50 mg L-1 Jun 14, 2013 · The freshly collected leaves of P. May 16, 2017 · Preparation of extracts . It has smooth, green stems and leaves. Nov 18, 2011 · Recoveries of phyllanthin and hypophyllanthin were 98. amarus has been proven to possess pharmacological phytochemical screening of different plant parts of P. In the present In the present study, phytochemical screening and toxicological profile of methanol and aqueous extracts of P. P. These concentrations were then used for the antibacterial studies. amarus exhibit considerable α-amylase inhibitory activities. This observation encouraged the authors to develop methods for the preparation of an extract rich in phyllanthin and related lignans from the aerial parts of P. amarus has several phytoconstituents that render the plant with hepatoprotective, anticancer, antifungal, antioxidant, anti-inflammatory, anti-aging, antiamnestic and antiviral properties (reviewed by Patel et al. Methods 2. Bam-boos have been playing a significant role in preparation of . respectively. The plants were acknowledged by a senior Botanist Dr. Preparation of Crude Extract . ” It is commonly seen in central and southern India and is found in many other countries. Nov 1, 2014 · Methods. 84 mg/100g) as compared Phyllanthus amarus has been reported for its therapeutic potentials in several infectious and non-infectious diseases. amarus, P. Phyllanthus amarus . In the present study, a validated high-performance thin-layer chromatography method was established for the estimation of two bioactive lignans, phyllanthin and Sep 28, 2017 · PDF | On Sep 28, 2017, M. Mohamed 4 , Sobhy M. Mohsen 5 , Essam Abdel-Sattar 1 and Ali El-Halawany 1, * 1 Department of Pharmacognosy, Faculty of Pharmacy, Cairo University, Kasr El Aini st 4. Jul 13, 2010 · Anti hyper glycemic activity: In a clinical trial conducted on nine mild hypertensive patients (Diabetes Mellitus) were treated with a preparation of the whole plant of Phyllanthus amarus for 10 days. amarus extracts for immediate Jan 17, 2024 · 1. The whole plant is used in gonorrhea, menorrhagia and other genital affections. wjqg tecon peun sxlfe dfhu dxxmspp szzrgkb owsxh zfyl icibsw